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GenDarwin Research GHK-CU lyophilized research peptide vial, CAS 89030-95-5

98.94%HPLC purity, as reported for this lot

HPLCPublished for lot P26070518-LR549315

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GHK-CU

Name: GHK-CU
Brand: GenDarwin Research
SKU: GD-GHKCU
Price: 59.00 USD
Availability: BackOrder

Copper(II) Complex of Glycyl-L-Histidyl-L-Lysine — Tripeptide-1 Copper

$59.00 $1.18 / mg On backorder — dispatches in 5–10 business days

Lyophilized powder HPLC purity 98.94% Research use only

GHK-Cu is a naturally occurring copper(II) chelate of the tripeptide Gly-His-Lys, originally isolated from human plasma. High-affinity Cu²⁺ coordination involves the N-terminal amine, the deprotonated Gly-His amide nitrogen, and the histidine imidazole N3. Research has characterised GHK-Cu as a modulator of integrin signalling, TGF-β gene expression, extracellular matrix biosynthesis (collagen I, III, IV; elastin; glycosaminoglycans), and suppression of pro-inflammatory cytokines including IL-6, TNF-α, and IL-1β in dermal fibroblast and endothelial cell model systems.

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PROPERTIES
Molecular Formula	C₁₄H₂₃CuN₆O₄+
Molecular Weight (g/mol)	402.92
Monoisotopic Mass (Da)	402.1077
Topological Polar Surface Area (Å²)	179
Complexity	428
XLogP (octanol-water partition)	Not computed by PubChem for this structure
Heavy Atom Count	25
H-Bond Donor Count	5
H-Bond Acceptor Count	7
Rotatable Bond Count	10
InChIKey	NZWIFMYRRCMYMN-ACMTZBLWSA-M
PubChem CID	71587328

All values above are taken from PubChem CID 71587328 and can be checked against that record.

2D Structure

CHEMICAL IDENTIFIERS
CAS Number	89030-95-5
PubChem CID	71587328
IUPAC Name	copper (2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoate
InChIKey	`NZWIFMYRRCMYMN-ACMTZBLWSA-M`
InChI	`InChI=1S/C14H24N6O4.Cu/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);/q;+2/p-1/t10-,11-;/m0./s1`
SMILES	`C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)[O-])NC(=O)CN.[Cu+2]`

Identifiers retrieved from PubChem CID 71587328.

HPLC purity report Sample lot

GHK-CU

Lot: P26070518-LR549315
SKU: GD-GHKCU

98.94% main peak, area %

10.577 minMain peak retention

1.0594%All other peaks

0.6067%Largest single impurity

4Peaks integrated

Drawn from the integration table below. Each peak sits at its reported retention time and is scaled so its height and area match the report; the peak shape is modelled and the baseline is flat, so this represents the reported integration rather than the raw detector file. Only the peaks the report lists are drawn. The lighter trace is the same data at 10× vertical zoom, because the impurity peaks are a fraction of a percent of the main peak.

Integration table as reported

#	Ret. time	Height	Area	Area %
1	7.445	12638.426	155456.203	0.6067
2	10.577	435276.188	25351972.000	98.9406
3	13.822	1205.485	34210.148	0.1335
4	20.302	2883.575	81798.102	0.3192

Retention time in minutes. Height and area are the report’s own values and units. Method wording is normalised for units and spelling; every value is as reported.

Method as reported

Column	4.6×250 mm, Venusil XBP-C18
Mobile phase A	0.1% trifluoroacetic acid in acetonitrile
Mobile phase B	0.1% trifluoroacetic acid in water
Flow rate	1.0 mL/min
Detection	220 nm
Injection volume	5 µL

Time	A	B
0.01min	2%	98%
25min	2%	98%
25.1min	100%	0%
30min	Stop

Identity verified against PubChem, not a measurement of this lot

CAS number: 89030-95-5
Molecular formula: C₁₄H₂₃CuN₆O₄⁺
Molecular weight: 402.92 g/mol
Monoisotopic mass: 402.1077 Da
InChIKey: NZWIFMYRRCMYMN-ACMTZBLWSA-M
PubChem CID: 71587328

Corrections and queries 1 corrected

Field	On the supplier document	Here	Why
What the figure covers	purity only	stated on the page	The method runs in 0.1% trifluoroacetic acid, which dissociates copper from the peptide, so the figure is the purity of the GHK peptide and not a copper assay. A copper content result has been requested.

A measured result is never rewritten. Where a reported figure does not stand up, it is shown as printed and marked as queried.

Sample lot. This is the report supplied with the sample of this compound. A production lot ships with its own report, published here in the same form and indexed by its own lot number.

Run in 0.1% TFA, which dissociates copper: this figure is the purity of the GHK peptide, not a copper assay.

Every analytical figure above is transcribed from the supplier’s report for lot P26070518-LR549315. Identity is the PubChem record, which can be checked independently. Purity is the main peak’s share of integrated peak area at the detection wavelength, so it measures related impurities. Water, salts and counter-ions are not part of it. These are the supplier’s release documents, not independent third-party tests.

This product is sold exclusively for in vitro and laboratory research use. It has not been evaluated by the FDA. Not approved for diagnostic, therapeutic, or veterinary use.

GHK-CU

2D Structure

Integration table as reported

Method as reported

Identity verified against PubChem, not a measurement of this lot

Corrections and queries 1 corrected

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