Kisspeptin-10

Name: Kisspeptin-10
Brand: GenDarwin Research
SKU: GD-KISS
Price: 69.00 USD
Availability: BackOrder

GPR54/KISS1R Receptor Agonist Decapeptide (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂)

$69.00 $13.80 / mg On backorder — dispatches in 5–10 business days

Lyophilized powder HPLC purity 98.61% Research use only

Kisspeptin-10 is a synthetic C-terminally amidated decapeptide (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂) corresponding to residues 45–54 of the KISS1 gene product. It binds with high affinity to GPR54/KISS1R (Kd ~0.04–2.3 nM), activating Gq/11-coupled Ca²⁺ mobilisation, ERK1/2 phosphorylation, and downstream modulation of GnRH neuronal secretion. Research applications include HPG-axis neuroendocrine circuitry studies, GPR54 receptor pharmacology, angiogenic signalling models, and in vitro tumour cell migration and adhesion paradigms.

Select size

Price breaks
Buy 3 −5%
Buy 5 −8%
Buy 10 −10%

Quantity totals add up across every compound in your cart, not per product.

On backorder — dispatches in 5–10 business days, then ships.

I understand this item is on backorder and will dispatch in 5–10 business days. I can cancel for a full refund any time before it ships.

PROPERTIES
Molecular Formula	C₆₃H₈₃N₁₇O₁₄
Molecular Weight (g/mol)	1302.4
Monoisotopic Mass (Da)	1301.6305
Topological Polar Surface Area (Å²)	538
Complexity	2590
XLogP (octanol-water partition)	-1.9
Heavy Atom Count	94
H-Bond Donor Count	18
H-Bond Acceptor Count	16
Rotatable Bond Count	38
InChIKey	RITKWYDZSSQNJI-INXYWQKQSA-N
PubChem CID	25240297

All values above are taken from PubChem CID 25240297 and can be checked against that record.

2D Structure

CHEMICAL IDENTIFIERS
CAS Number	374675-21-5
PubChem CID	25240297
IUPAC Name	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
InChIKey	`RITKWYDZSSQNJI-INXYWQKQSA-N`
InChI	InChI=1S/C63H83N17O14/c1-34(2)24-45(58(90)74-43(18-11-23-70-63(68)69)57(89)75-44(54(67)86)26-35-12-5-3-6-13-35)73-53(85)32-72-56(88)46(27-36-14-7-4-8-15-36)77-62(94)50(33-81)80-61(93)49(30-52(66)84)79-59(91)47(28-38-31-71-42-17-10-9-16-40(38)42)78-60(92)48(29-51(65)83)76-55(87)41(64)25-37-19-21-39(82)22-20-37/h3-10,12-17,19-22,31,34,41,43-50,71,81-82H,11,18,23-30,32-33,64H2,1-2H3,(H2,65,83)(H2,66,84)(H2,67,86)(H,72,88)(H,73,85)(H,74,90)(H,75,89)(H,76,87)(H,77,94)(H,78,92)(H,79,91)(H,80,93)(H4,68,69,70)/t41-,43-,44-,45-,46-,47-,48-,49-,50-/m0/s1
SMILES	`CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC5=CC=C(C=C5)O)N`

Identifiers retrieved from PubChem CID 25240297.

HPLC purity report Sample lot

Kisspeptin-10

Lot: P260710-YS205403
SKU: GD-KISS

98.61% main peak, area %

9.785 minMain peak retention

1.3838%All other peaks

0.8878%Largest single impurity

3Peaks integrated

Drawn from the integration table below. Each peak sits at its reported retention time and is scaled so its height and area match the report; the peak shape is modelled and the baseline is flat, so this represents the reported integration rather than the raw detector file. Only the peaks the report lists are drawn. The lighter trace is the same data at 50× vertical zoom, because the impurity peaks are a fraction of a percent of the main peak.

Integration table as reported

#	Ret. time	Height	Area	Area %
1	6.935	2485	24601	0.496
2	9.785	307845	4890642	98.61
3	10.267	3357	44028	0.8878

Retention time in minutes. Height and area are the report’s own values and units. Method wording is normalised for units and spelling; every value is as reported.

Method as reported

Column	250 × 4.6 mm, ChromCore 120-C18-5 µm
Mobile phase A	0.1% TFA in water
Mobile phase B	0.1% TFA in acetonitrile
Flow rate	1.0 mL/min
Detection	220 nm
Injection volume	10 µL

Time	A	B
0.1min	74%	26%
25.0min	49%	51%
25.1min	0%	100%
30.0min	Stop

Identity verified against PubChem, not a measurement of this lot

CAS number: 374675-21-5
Molecular formula: C₆₃H₈₃N₁₇O₁₄
Molecular weight: 1302.4 g/mol
Monoisotopic mass: 1301.6305 Da
InChIKey: RITKWYDZSSQNJI-INXYWQKQSA-N
PubChem CID: 25240297

Sample lot. This is the report supplied with the sample of this compound. A production lot ships with its own report, published here in the same form and indexed by its own lot number.

Every analytical figure above is transcribed from the supplier’s report for lot P260710-YS205403. Identity is the PubChem record, which can be checked independently. Purity is the main peak’s share of integrated peak area at the detection wavelength, so it measures related impurities. Water, salts and counter-ions are not part of it. These are the supplier’s release documents, not independent third-party tests.

This product is sold exclusively for in vitro and laboratory research use. It has not been evaluated by the FDA. Not approved for diagnostic, therapeutic, or veterinary use.

Kisspeptin-10

2D Structure

Integration table as reported

Method as reported

Identity verified against PubChem, not a measurement of this lot

Related compounds