DSIP

Name: DSIP
Brand: GenDarwin Research
SKU: GD-DSIP
Price: 59.00 USD
Availability: BackOrder

Delta Sleep-Inducing Peptide — Nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu; WAGGDASGE)

$59.00 $11.80 / mg On backorder — dispatches in 5–10 business days

Lyophilized powder HPLC purity 98.65% Research use only

Delta Sleep-Inducing Peptide (DSIP; Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) is an endogenous nonapeptide originally isolated from thalamus-stimulated rabbit cerebral venous blood, co-localising with ACTH, α-MSH, and glucagon-containing secretory cells. Research has characterised DSIP as a modulator of MAO-A activity, GABA-A receptor current potentiation, NMDA receptor-mediated current inhibition, and neuroendocrine secretion of corticotropin, somatostatin, and gonadotropin. Applied in circadian rhythm research and mitochondrial oxidative phosphorylation efficiency studies under hypoxic stress conditions.

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PROPERTIES
Molecular Formula	C₃₅H₄₈N₁₀O₁₅
Molecular Weight (g/mol)	848.8
Monoisotopic Mass (Da)	848.3301
Topological Polar Surface Area (Å²)	407
Complexity	1610
XLogP (octanol-water partition)	-7.1
Heavy Atom Count	60
H-Bond Donor Count	14
H-Bond Acceptor Count	16
Rotatable Bond Count	25
InChIKey	ZRZROXNBKJAOKB-GFVHOAGBSA-N
PubChem CID	68816

All values above are taken from PubChem CID 68816 and can be checked against that record.

2D Structure

CHEMICAL IDENTIFIERS
CAS Number	62568-57-4
PubChem CID	68816
IUPAC Name	(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
InChIKey	`ZRZROXNBKJAOKB-GFVHOAGBSA-N`
InChI	`InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1`
SMILES	`C[C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)N`

Identifiers retrieved from PubChem CID 68816.

HPLC purity report Sample lot

DSIP

Lot: P260725-LR055319
SKU: GD-DSIP

98.65% main peak, area %

13.31 minMain peak retention

1.349%All other peaks

1.1677%Largest single impurity

3Peaks integrated

Drawn from the integration table below. Each peak sits at its reported retention time and is scaled so its height and area match the report; the peak shape is modelled and the baseline is flat, so this represents the reported integration rather than the raw detector file. Only the peaks the report lists are drawn. The lighter trace is the same data at 50× vertical zoom, because the impurity peaks are a fraction of a percent of the main peak.

Integration table as reported

#	Ret. time	Height	Area	Area %
1	12.685	2261.117	48436.156	1.1677
2	13.310	210681.531	4092085.750	98.6510
3	14.308	887.022	7520.298	0.1813

Retention time in minutes. Height and area are the report’s own values and units. Method wording is normalised for units and spelling; every value is as reported.

Method as reported

Column	4.6×250 mm, Kromasil 100-5 C18
Mobile phase A	0.1% trifluoroacetic acid in acetonitrile
Mobile phase B	0.1% trifluoroacetic acid in water
Flow rate	1.0 mL/min
Detection	220 nm
Injection volume	5 µL

Time	A	B
0.01min	20%	80%
25min	45%	55%
25.1min	100%	0%
30min	Stop

Identity verified against PubChem, not a measurement of this lot

CAS number: 62568-57-4
Molecular formula: C₃₅H₄₈N₁₀O₁₅
Molecular weight: 848.82 g/mol
Monoisotopic mass: 848.3301 Da
InChIKey: ZRZROXNBKJAOKB-GFVHOAGBSA-N
PubChem CID: 68816

Corrections and queries 1 corrected

Field	On the supplier document	Here	Why
Compound name	DISP	DSIP	The sequence the report prints, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, is DSIP. 'DISP' is a typing error, as is 'Seuqence' on the same line.

A measured result is never rewritten. Where a reported figure does not stand up, it is shown as printed and marked as queried.

Sample lot. This is the report supplied with the sample of this compound. A production lot ships with its own report, published here in the same form and indexed by its own lot number.

Every analytical figure above is transcribed from the supplier’s report for lot P260725-LR055319. Identity is the PubChem record, which can be checked independently. Purity is the main peak’s share of integrated peak area at the detection wavelength, so it measures related impurities. Water, salts and counter-ions are not part of it. These are the supplier’s release documents, not independent third-party tests.

This product is sold exclusively for in vitro and laboratory research use. It has not been evaluated by the FDA. Not approved for diagnostic, therapeutic, or veterinary use.

DSIP

2D Structure

Integration table as reported

Method as reported

Identity verified against PubChem, not a measurement of this lot

Corrections and queries 1 corrected

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